Lupus is a prominent name among the myriad chronic inflammatory conditions where the body’s immune system begins attacking its own tissues. This autoimmune condition can impact virtually any organ of the body. It is incurable, the clinical presentation is widely variable with sometimes debilitating flares and the complications, potentially fatal in some cases when left untreated. Among other organs, Kidneys are a prime target here. So, as a portal dedicated to nephrology, let us walk you through the what-why-how of this challenging autoimmune disorder with specific focus on Lupus Nephritis – its kidney chapter. It is Lupus Awareness Month (May) after all!
COVID19 Vaccines vs Evusheld ® vs Mask: What works the best in Immunocompromised?
COVID19 prevention has been a tough nut to crack especially in the Immunocompromised. On one hand, the COVID19 vaccines fell short in patients with moderate to severe weakening of immunity. This included kidney patients with advanced pre-dialysis state, those on dialysis and post-transplant. On the other, in certain kidney patient cohorts who did develop traceable immune response to the vaccines ended up with a flaring of pre-existing underlying autoimmune kidney diseases like IgA Nephropathy.
Then we have Evusheld ® – drug maker AstraZeneca’s new long acting monoclonal antibody combo shot. This antibody drug (generic name: AZD7442) was granted an Emergency Use Authorization by the USFDA on December 8th, 2021. With its “ready-made immune protection”, this long acting antibody (LAAB) drug shows promise in preventing symptomatic COVID19 in immunocompromised patients (just like vaccines do in immunocompetent). However, only time will tell how well it performs on-field. Read more here.
But then, amidst this steady inflow of pharmacological strategies to ward-off COVID19, if something has managed to survive it’s the utility of the humble face mask. Of-course, other COVID safe practices like following strict hygiene protocols and avoiding crowds go hand-in-hand.
So what works the best?
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Kidney Transplant: Before the surgery – II
Hello kidney warriors & knowledge seekers! Today, we continue from our previous article on all steps that kidney patients & kidney donors need to follow before getting admitted to the hospital for a Transplant surgery.
The article today explains the basic workflow involved for every kidney patient scheduled for a transplant & their donor starting from hospital admission until they finally get to go under the knife.
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