Glomerular Filtration Rate (GFR)

If you are a member of the kidney community – whether as a patient, caregiver, advocate or knowledge seeker – it is likely that you have come across the term “Glomerular Filtration Rate” or more commonly, the GFR. Perhaps you are also aware that this term broadly relates to your kidney’s functional capacity.

GFR Kidney But do you completely understand what GFR really is?

GFR Kidney How does your medical team clinically assess the GFR for your kidneys?

GFR Kidney How valid is it throughout your CKD journey?

GFR Kidney And is it always indicative of the true health status of your kidneys?

All these are some very pertinent questions that each member of the Kidney Community, especially the patients & caregivers must thoroughly know the answers to. And that is exactly what we are here to help you with, today. Continue reading “Glomerular Filtration Rate (GFR)”

Protein in Urine: What, How & Why

Proteinuria

 

WHAT IS PROTEINURIA?

The leakage of Plasma Protein in urine is technically termed as “Proteinuria” (pronounced as pro-teen-you-reah). These proteins are NOT the usual nutrient that you obtain from food. These are a different class of Proteins specially made by your Liver.

Plasma Proteins normally circulate in your bloodstream & help with a range of functions essential to keep you alive. Urine samples with Protein tend to be visibly foamy / frothy akin to the kind that you get after dissolving detergents in water. The extent of foam will certainly vary with the extent of protein leakage.

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Healthy Kidneys prevent Blood & Protein in Urine. But how?!

Protein blood barrier

Normally, Urine produced by healthy kidneys is a cocktail of toxic waste products of cellular metabolism, a host of minerals, salts, smelly organic compounds & excess water. (Find the complete normal urine composition here). These components begin to get together to form Urine once healthy kidney micro-filters “strain” our blood through themselves. These micro-filters are uber-selective with what they “let-out” into the urine. This is such that, all blood cells & “plasma” proteins remain in the bloodstream while the wastes & excesses purge themselves out.

But what makes these Kidney Micro-filters that selective against leakage of blood cells & protein in urine?

LET’S DISSECT!

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