Poor response to COVID Vaccine in Kidney Patients: Decode the Science-Understand your Options

COVID19 Vaccine Response in immunocompromised CKD Dialysis Post Kidney Transplant patients | All Things Kidney | All Things Kidney Official | allthingskidney.com | Dr Sparshita Nag | Kidney Disease

COVID19 vaccine inoculations are the best possible protection for most health profiles that science offers against this pandemic menace. However, as we know, COVID vaccines in their initially recommended dose schedules proved less effective in immunocompromised individuals. This was irrespective of whether  poor immunity resulted from a medical condition or due to immuno-suppressive medication. Patients with advanced Chronic Kidney Disease & Kidney Transplant recipients are a prominent subgroup in this population subset of the “Vaccine Helpless”.

So how did poor immunity in kidney patients impact vaccine effectiveness?

◾ Will repeated immune challenge with extra doses as part of primary vaccine series truly help all kidney patients? How tenable is it?

◾ Any better alternatives to garner adequate immune protection for our cohort without going overboard with the “immune challenge” and/or inviting side-effects of major concern?

 

Read on to decode the relevant science and understand your options for adequate immune protection against COVID-19.

(DISCLAIMER: The article is purely a medically feasible insight on current evidence from peer-reviewed scientific literature on COVID-19 vaccine efficiency, its shortcomings & potential relevant alternative pharmacological solutions w.r.t. patients with chronic kidney disease. The intention is to place the facts as they are with due respect to Science. It is not intended to promote any vaccine hesitancy or support anti-vaxxer views. It does not represent any political positioning either.)

Continue reading “Poor response to COVID Vaccine in Kidney Patients: Decode the Science-Understand your Options”

Kidney Transplant Complications

Kidney Transplant saves precious lives. But it also qualifies as a major surgery involving complicated procedures. This holds true for both the donor kidney retrieval surgery and implantation of the donor kidney into the recipient (patient). Quite naturally, both surgeries may entail risks / possible complications during and after the procedures, both in the short & long term. It is these possible risks/complications of Kidney Transplant are what we aim to walk you through, today.

Complications of Kidney Transplant cover pic | All Things Kidney Official | allthingskidney.com

We will first cover the risk-profile associated with Kidney Donation followed by that for the Kidney Recipient. The article presents the list of complications as per the time points at which they usually appear after the surgery. Read on to get a comprehensive insight on the what-why-how of these complications below.

NOTE: This article only covers complications from the kidney transplant procedure. Adverse effects expected from anti-rejection & other medications that a kidney recipient is put on, will be explained in a separate article.

Continue reading “Kidney Transplant Complications”

Kidney Transplant: The Operation

Kidney Transplant is the surgical procedure to trans-fer a healthy, matched kidney from a willing donor & im-plant it in a patient with kidney failure to prolong the patient’s life. Till date, this is the best treatment for the majority of patients with kidney failure due to Chronic Kidney Disease.

Kidney Transplant
Source: Nebraska Medicine
 

Team ATK has always advocated in favour of gaining a thorough understanding of your disease process & treatments.

Keeping in sync with this principle, our article today dissects the kidney transplant surgery for you. We present the topic in two parts as below:

Continue reading “Kidney Transplant: The Operation”

Kidney Transplant: Before the surgery – I

Kidney transplant 

Every patient with End Stage Renal Disease (ESRD) or in other words, Kidney failure needs to go on treatments that would “fill the gaps” in the errant functioning of the unwell kidney or completely replace it with healthy functioning. Dialysis is a way to fill the gaps while a Kidney Transplant is a complete replacement.

In our previous article, we explained the bare basics of a Kidney Transplant.

This article covers an outline of what an average pre-transplant preparation for the patient and the kidney donor may entail.

Continue reading “Kidney Transplant: Before the surgery – I”

Kidney Transplant – Basics


Contents


 

1. What is Kidney Transplant?

Kidneys are essential for sustaining life. Individuals who end up with very little or almost no kidney function, either due to an incurable disease, birth defect or extensive injury, require a solution to regain/assist with their kidney function. Kidney Transplant is one of the methods to do so.

This involves a surgical procedure of “transferring” a healthy, matched kidney from a willing donor to “implant” it in the belly of the patient requiring the organ. Hence the name, Transplant.

Here, the donor kidney is securely removed with Continue reading “Kidney Transplant – Basics”

Blood in Urine: Can it be resolved?

Haematuria (Red blood cells in urine) is not a disease in itself. It is a “sign” that points to an abnormality within your body.

The treatment approach towards haematuria would require a confirmed diagnosis of the underlying cause and adopting relevant medical and/or corrective surgical approaches. Whether it can be resolved completely or not would entirely depend on its root cause.

Link blood in urine

Presenting here, the general pointers that guide your treatment plan for patients with Haematuria.

Hand symbol blood in urine Continue reading “Blood in Urine: Can it be resolved?”

Chronic Kidney Disease — The Basics

What is Chronic Kidney Disease (CKD)?

Chronic kidney disease (CKD), also called Chronic Renal Disease is defined as the gradual loss of kidney function over at least 3 months to several years “since the time of organ insult by the root disease” (not since symptoms appear).

When kidney function is jeopardized in a gradual but progressive manner, they will be unable to perform any of their designated functions properly, that they otherwise normally carry out to keep you alive and kicking!

 

What causes CKD?

CKD is an umbrella term for a multitude of medical conditions that can affect and gradually damage the kidney during their natural course in our body.



 

The following diseases & conditions have been found to cause Chronic Kidney Disease:

Continue reading “Chronic Kidney Disease — The Basics”

Love Thy Kidneys!

I have been thinking about this for a while now. How would it be, if we decided to assign a gender to our organs based on their “inherent nature”. Without hesitation, I’ll call our kidneys, female.

Somewhat like our Mums actually! (Yeah, you read that right).

This cute, smooth, bean-shaped major organ-pair is:

  •  “Effortlessly multitasking”
  •  “Hygiene-conscious”
  •  “Meticulous”
  •  “Complex yet super-organized”
  •  “Layered & difficult to understand at times”
  •  “Fantastically resilient to all external stress” (up until it gets unbearable of course)

and above all

  •  “Holds the entire organ-family from “falling apart”

 

All quintessential mommy traits eh?

Welcome Smiley kidneys in ATK

Time to bring kidneys to the limelight for all she’s worth then?

So, watch this space for more to obtain a medically accurate understanding of this beautiful but highly underrated organ.



In this portal, you will find: –

So what are you waiting for?

Explore https://www.allthingskidney.com today.

Unleash the power of knowing. Beat the apprehension/confusion/ignorance surrounding kidneys in health & disease.

Stay well, all of you!

 



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